Pain Management Therapeutics Market to 2019 - Impact of Patent Expiries Offset by Demand for Neuropathic and Rheumatoid Pain Medications and Strong Pipeline -





Published: July 2013 | Pages: 186 | Format: PDF

 Summary 

GBI Research’s report “Pain Management Therapeutics Market to 2019 - Impact of Patent Expiries Offset by Demand for Neuropathic and Rheumatoid Pain Medications and Strong Pipeline“ provides insights and analysis into the market. Pain is a widespread problem across the world. More than 25% of the total population suffers from some clinically significant pain in a year. Since pain considerably affects day-to-day activities in life, its management presents a considerable challenge for physicians. Inadequate pain control remains a major problem across the world. There is an urgent and unmet need to manage these pain-related problems accurately. Currently, the management of pain is not efficient due to low diagnosis and prescription rates. In many cases, such as cancer pain, 50% of the people taking medicines are not satisfied with the results. This is primarily due to the absence of a perfect pain management solution. Pain management can be most effective only when the underlying disease conditions are cured. However, there is no treatment that offers absolute relief for the indications covered in this report. The medications given for these indications are more for modifying the disease symptoms than offering complete relief from pain. The combination of under-managed pain, low awareness, and fear of addiction to some classes of pain medication is preventing people suffering pain from seeking treatment 100% of the time. 

 Scope 

  •  Overview of the pain management market by analyzing the revenue, Annual Cost of Therapy (ACT) and treatment usage pattern across the top seven markets, which are the US, the UK, France, Germany, Spain, Italy and Japan. 
  •  Therapeutic landscape of the pain management therapeutics market and includes detailed market sizing and analysis of the trends in eight indications, which are fibromyalgia, neuropathic pain, cancer pain, Osteoarthritis (OA) pain, Rheumatoid Arthritis (RA) pain, migraine, Low Back Pain (LBP) and post-operative pain. 
  •  Geographical landscape of the pain management therapeutics market in the top seven markets, which are the US, the UK, France, Germany, Spain, Italy and Japan. 
  •  Detailed pipeline analysis of the pain management market (as of April 2013). The section also contains detailed analyses of the most promising pipeline molecules. 
  •  Profiles of the top companies operating in the pain management therapeutics market. 
  •  List of strategic consolidations, such as M&A deals, licensing agreements and partnership deals that took place in the global pain management therapeutics market between 2007 and 2013. 

 Reasons to buy 

  •  Align your product portfolio to the markets with high growth potential. 
  •  Develop market-entry and market expansion strategies by identifying the potential region and therapeutic segments poised for strong growth. 
  •  Devise a more tailored country strategy through the understanding of key drivers and barriers of the region’s pain management therapeutics market. 
  •  Develop key strategic initiatives by understanding the key focus areas and top selling pain management therapeutics molecules of leading companies. 
  •  Accelerate and strengthen your market position by identifying key companies for mergers, acquisitions and strategic partnerships. 

 

 1 Table of Contents 6 

 1.1 List of Tables 10 

 1.2 List of Figures 13 

 2 Pain Management Therapeutics Market to 2019 - Introduction 16 

 3 Pain Management Therapeutics Market to 2019 - Market Overview 17 

 3.1 Introduction 17 

 3.2 World Health Organization Pain Ladder 18 

 3.3 Risk Evaluation and Mitigation Strategy 19 

 3.4 Revenue 20 

 3.5 Major Marketed Pain Management Drugs 21 

 3.5.1 Abstral (fentanyl citrate) 21 

 3.5.2 Celebrex (celecoxib) 22 

 3.5.3 Cymbalta (duloxetine) 23 

 3.5.4 Exparel (Bupivacaine ER) 24 

 3.5.5 Lidoderm (lidocaine patch) 25 

 3.5.6 Lyrica (pregabalin) 26 

 3.5.7 Nucynta ER (tapentadol ER) 27 

 3.5.8 Qutenza (capsaicin) 28 

 3.5.9 Savella (milnacipran hydrochloride) 29 

 3.5.10 Vimovo (esomeprazole magnesium + naproxen) 30 

 3.5.11 Voltaren Gel (diclofenac sodium) 31 

 3.6 Annual Cost of Therapy 32 

 3.7 Treatment Usage Patterns 33 

 3.7.1 Prevalence Population 34 

 3.7.2 Diagnosed Population 34 

 3.7.3 Prescription Population 34 

 3.8 Drivers and Restraints of the Pain Management Therapeutics Market 35 

 3.8.1 Drivers 35 

 3.8.2 Restraints 36 

 4 Pain Management Therapeutics Market to 2019 - Therapeutic Landscape 37 

 4.1 Pain Management Therapeutics Market for Fibromyalgia 37 

 4.1.1 Introduction 37 

 4.1.2 Revenue 37 

 4.1.3 Annual Cost of Therapy 39 

 4.1.4 Treatment Flow Algorithm 40 

 4.1.5 Treatment Usage Pattern 41 

 4.1.6 Geographical Segmentation 43 

 4.1.7 Drivers and Restraints for the Fibromyalgia Market 44 

 4.1.8 Drivers 45 

 4.1.9 Restraints for the Fibromyalgia Pain Relief Market 45 

 4.2 Pain Management Therapeutics for Neuropathic Pain 46 

 4.2.1 Introduction 46 

 4.2.2 Revenue 46 

 4.2.3 Annual Cost of Therapy 48 

 4.2.4 Treatment Flow Algorithm 49 

 4.2.5 Treatment Usage Pattern 50 

 4.2.6 Geographical Segmentation 52 

 4.2.7 Drivers and Restraints for the Neuropathic Pain Market 53 

 4.2.8 Drivers 53 

 4.2.9 Restraints 54 

 4.3 Pain Management Therapeutics Market for Migraine 55 

 4.3.1 Introduction 55 

 4.3.2 Revenue 55 

 4.3.3 Annual Cost of Therapy 57 

 4.3.4 Treatment Flow Algorithm 58 

 4.3.5 Treatment Usage Pattern 59 

 4.3.6 Geographical Segmentation 61 

 4.3.7 Drivers and Restraints for the Migraine Market 62 

 4.3.8 Drivers 62 

 4.3.9 Restraints 62 

 4.4 Pain Management Therapeutics Market for Cancer Pain 63 

 4.4.1 Introduction 63 

 4.4.2 Revenue 64 

 4.4.3 Annual Cost of Therapy 65 

 4.4.4 Treatment Flow Algorithm 66 

 4.4.5 Treatment Usage Pattern 67 

 4.4.6 Geographical Segmentation 69 

 4.4.7 Drivers and Restraints for the Cancer Pain Market 70 

 4.4.8 Drivers 70 

 4.4.9 Restraints 71 

 4.5 Pain Management Therapeutics Market for Osteoarthritis Pain 72 

 4.5.1 Introduction 72 

 4.5.2 Revenue 72 

 4.5.3 Annual Cost of Therapy 74 

 4.5.4 Treatment Flow Algorithm 75 

 4.5.5 Treatment Usage Pattern 76 

 4.5.6 Geographical Segmentation 78 

 4.5.7 Drivers and Restraints for the Osteoarthritis Pain Market 79 

 4.5.8 Drivers 79 

 4.5.9 Restraints 79 

 4.6 Pain Management Therapeutics Market for Rheumatoid Arthritis Pain 80 

 4.6.1 Introduction 80 

 4.6.2 Revenue 80 

 4.6.3 Annual Cost of Therapy 82 

 4.6.4 Treatment Flow Algorithm 83 

 4.6.5 Treatment Usage Pattern 84 

 4.6.6 Geographical Segmentation 86 

 4.6.7 Drivers and Restraints for the Rheumatoid Arthritis Market 87 

 4.6.8 Drivers 87 

 4.6.9 Restraints 87 

 4.7 Pain Management Therapeutics Market for Low Back Pain 88 

 4.7.1 Introduction 88 

 4.7.2 Revenue 88 

 4.7.3 Annual Cost of Therapy 90 

 4.7.4 Treatment Flow Algorithm 91 

 4.7.5 Treatment Usage Pattern 92 

 4.7.6 Geographical Segmentation 94 

 4.7.7 Drivers and Restraints for the Low Back Pain Market 95 

 4.7.8 Drivers 95 

 4.7.9 Restraints 95 

 4.8 Pain Management Therapeutics Market for Post-operative Pain 96 

 4.8.1 Introduction 96 

 4.8.2 Revenue 97 

 4.8.3 Annual Cost of Therapy 98 

 4.8.4 Treatment Flow Algorithm 99 

 4.8.5 Treatment Usage Pattern 100 

 4.8.6 Geographical Segmentation 102 

 4.8.7 Drivers and Restraints for the Post-operative Pain Market 103 

 4.8.8 Drivers 103 

 4.8.9 Restraints 103 

 5 Pain Management Therapeutics Market to 2019 - Geographical Landscape 104 

 5.1 The US 105 

 5.1.1 Revenue 105 

 5.1.2 Annual Cost of Therapy 106 

 5.1.3 Treatment Usage Pattern 107 

 5.2 Top Five European Countries 109 

 5.2.1 Revenue 109 

 5.2.2 Annual Cost of Therapy 110 

 5.2.3 Treatment Usage Pattern 111 

 5.3 Japan 113 

 5.3.1 Revenue 113 

 5.3.2 Annual Cost of Therapy 114 

 5.3.3 Treatment Usage Pattern 115 

 6 Pain Management Therapeutics Market to 2019 - Asia-Pacific and China 117 

 6.1 India 117 

 6.1.1 Regulatory Landscape 117 

 6.1.2 Marketed Products 120 

 6.1.3 Company Profiling 121 

 6.2 China 125 

 6.2.1 Regulatory Landscape 125 

 6.2.2 Marketed Products 128 

 6.2.3 Company Profiling 128 

 6.3 Australia 129 

 6.3.1 Regulatory Landscape 129 

 6.3.2 Marketed Products 130 

 6.3.3 Company Profiling 131 

 7 Pain Management Therapeutics Market to 2019 - Pipeline Analysis 134 

 7.1 Introduction 134 

 7.1.1 Research and Development Pipeline – Fibromyalgia 136 

 7.1.2 Research and Development Pipeline – Neuropathic Pain 138 

 7.1.3 Research and Development Pipeline – Migraine 143 

 7.1.4 Research and Development Pipeline – Cancer Pain 146 

 7.1.5 Research and Development Pipeline – Osteoarthritis Pain 148 

 7.1.6 Research and Development Pipeline – Low Back Pain 150 

 7.1.7 Research and Development Pipeline – Post-operative Pain 152 

 7.2 Profiles of Key Late-Stage Drugs in the Pain Management Therapeutics Market 154 

 7.2.1 AmiKet 154 

 7.2.2 Civanex 155 

 7.2.3 Droxidopa 156 

 7.2.4 Posidur 157 

 7.2.5 Sativex 158 

 7.2.6 TNX-102 159 

 7.2.7 Tetrodotoxin 160 

 8 Pain Management Therapeutics Market to 2019 - Competitive Landscape 161 

 8.1 Pfizer Inc 161 

 8.1.1 Overview 161 

 8.1.2 Product Profile 161 

 8.2 Johnson & Johnson 162 

 8.2.1 Overview 162 

 8.2.2 Product Portfolio 162 

 8.3 Endo Pharmaceuticals 163 

 8.3.1 Overview 163 

 8.3.2 Product Portfolio 163 

 8.4 Forest Laboratories 164 

 8.4.1 Overview 164 

 8.4.2 Product Portfolio 164 

 8.5 Eli Lilly 164 

 8.5.1 Overview 164 

 8.5.2 Product Portfolio 165 

 8.6 Teva Pharmaceuticals (Cephalon, Inc.) 165 

 8.6.1 Overview 165 

 8.6.2 Product Portfolio 165 

 8.7 Purdue Pharma 166 

 8.7.1 Overview 166 

 8.7.2 Product Portfolio 166 

 9 Pain Management Therapeutics Market to 2019 - Strategic Consolidations 168 

 9.1 Overview 168 

 9.1.1 M&A Deals by Year 168 

 9.1.2 M&A Deals by Indication 169 

 9.1.3 Recent Deals 170 

 9.2 Licensing Agreements 171 

 9.2.1 Deals by Year 171 

 9.2.2 Deals by Indication 172 

 9.2.3 Deals by Phase 173 

 9.2.4 Recent Licensing Deals 174 

 9.3 Partnership Deals 175 

 9.3.1 Deals by Year 175 

 9.3.2 Deals by Indication 176 

 9.3.3 Recent Partnership Deals 177 

 10 Management Therapeutics Market to 2019 - Appendix 178 

 10.1 Market Definitions 178 

 10.2 Abbreviations 178 

 10.3 Bibliography 180 

 10.4 Research Methodology 182 

 10.4.1 Coverage 182 

 10.4.2 Secondary Research 182 

 10.4.3 Primary Research 183 

 10.5 Therapeutic Landscape 183 

 10.5.1 Market 185 

 10.6 Geographical Landscape 186 

 10.7 Pipeline Analysis 186 

 10.8 Competitive Landscape 186 

 10.8.1 Expert Panel Validation 186 

 10.9 Contact Us 186 

 10.10 Disclaimer 186 

  

 1.1 List of Tables 

 Table 1: Pain Management Therapeutics Market, Top Seven Markets, Revenue ($bn), 2006–2012 20 

 Table 2: Pain Management Therapeutics Market, Top Seven Markets, Revenue Forecast ($bn), 2012–2019 20 

 Table 3: Pain Management Therapeutics Market, Top Seven Markets, Annual Cost of Therapy ($), 2006–2012 32 

 Table 4: Pain Management Therapeutics Market, Top Seven Markets, Annual Cost of Therapy Forecast ($), 2012–2019 32 

 Table 5: Pain Management Therapeutics Market, Top Seven Markets, Treatment Usage Pattern (million), 2006–2012 33 

 Table 6: Pain Management Therapeutics Market, Top Seven Markets, Treatment Usage Pattern Forecast (million), 2012–2019 34 

 Table 7: Pain Management Therapeutics Market, Top Seven Markets, Fibromyalgia, Revenue ($bn), 2006–2012 38 

 Table 8: Pain Management Therapeutics Market, Top Seven Markets, Fibromyalgia, Revenue Forecast ($bn), 2012–2019 38 

 Table 9: Pain Management Therapeutics Market, Top Seven Markets, Fibromyalgia, Annual Cost of Therapy ($), 2006–2012 39 

 Table 10: Pain Management Therapeutics Market, Top Seven Markets, Fibromyalgia, Annual Cost of Therapy Forecast ($), 2012–2019 39 

 Table 11: Pain Management Therapeutics Market, Top Seven Markets, Fibromyalgia, Treatment Usage Pattern (Million), 2006–2012 41 

 Table 12: Pain Management Therapeutics Market, Top Seven Markets, Fibromyalgia, Treatment Usage Pattern Forecast (Million), 2012–2019 41 

 Table 13: Pain Management Therapeutics Market, Top Seven Markets, Neuropathic Pain, Revenue ($bn), 2006–2012 46 

 Table 14: Pain Management Therapeutics Market, Top Seven Markets, Neuropathic Pain, Revenue Forecast ($bn), 2012–2019 47 

 Table 15: Pain Management Therapeutics Market, Top Seven Markets, Neuropathic Pain, Annual Cost of Therapy ($), 2006–2012 48 

 Table 16: Pain Management Therapeutics Market, Top Seven Markets, Neuropathic Pain, Annual Cost of Therapy Forecast ($), 2012–2019 48 

 Table 17: Pain Management Therapeutics Market, Top Seven Markets, Neuropathic Pain, Treatment Usage Pattern (million), 2006–2012 50 

 Table 18: Pain Management Therapeutics Market, Top Seven Markets, Neuropathic Pain, Treatment Usage Pattern Forecast (million), 2012–2019 50 

 Table 19: Pain Management Therapeutics Market, Top Seven Markets, Migraine, Revenue ($bn), 2006–2012 55 

 Table 20: Pain Management Therapeutics Market, Top Seven Markets, Migraine, Revenue Forecast ($bn), 2012–2019 56 

 Table 21: Pain Management Therapeutics Market, Top Seven Markets, Migraine, Annual Cost of Therapy ($), 2006–2012 57 

 Table 22: Pain Management Therapeutics Market, Top Seven Markets, Migraine, Annual Cost of Therapy Forecast ($), 2012–2019 57 

 Table 23: Pain Management Therapeutics Market, Top Seven Markets, Migraine, Treatment Usage Pattern (million), 2006–2012 59 

 Table 24: Pain Management Therapeutics Market, Top Seven Markets, Migraine, Treatment Usage Pattern Forecast (million), 2012–2019 60 

 Table 25: Pain Management Therapeutics Market, Top Seven Markets, Cancer Pain, Revenue ($bn), 2006–2012 64 

 Table 26: Pain Management Therapeutics Market, Top Seven Markets, Cancer Pain, Revenue Forecast ($bn), 2012–2019 64 

 Table 27: Pain Management Therapeutics Market, Top Seven Markets, Cancer Pain, Annual Cost of Therapy ($), 2006–2012 65 

 Table 28: Pain Management Therapeutics Market, Top Seven Markets, Cancer Pain, Annual Cost of Therapy Forecast ($), 2012–2019e 65 

 Table 29: Pain Management Therapeutics Market, Top Seven Markets, Cancer Pain, Treatment Usage Pattern (million), 2006–2012 67 

 Table 30: Pain Management Therapeutics Market, Top Seven Markets, Cancer Pain, Treatment Usage Pattern Forecast (million), 2012–2019 67 

 Table 31: Pain Management Therapeutics Market, Top Seven Markets, Osteoarthritis Pain, Revenue ($bn), 2006–2012 73 

 Table 32: Pain Management Therapeutics Market, Top Seven Markets, Osteoarthritis Pain, Revenue Forecast ($bn), 2012–2019 73 

 Table 33: Pain Management Therapeutics Market, Top Seven Markets, Osteoarthritis Pain, Annual Cost of Therapy ($), 2006–2012 74 

 Table 34: Pain Management Therapeutics Market, Top Seven Markets, Osteoarthritis Pain, Annual Cost of Therapy Forecast ($), 2012–2019 74 

 Table 35: Pain Management Therapeutics Market, Top Seven Markets, Osteoarthritis Pain, Treatment Usage Pattern (million), 2006–2012 76 

 Table 36: Pain Management Therapeutics Market, Top Seven Markets, Osteoarthritis Pain, Treatment Usage Pattern Forecast (million), 2012–2019 76 

 Table 37: Pain Management Therapeutics Market, Top Seven Markets, Rheumatoid Arthritis Pain, Revenue ($bn), 2006–2012 80 

 Table 38: Pain Management Therapeutics Market, Top Seven Markets, Rheumatoid Arthritis Pain, Revenue Forecast ($bn), 2012–2019 81 

 Table 39: Pain Management Therapeutics Market, Top Seven Markets, Rheumatoid Arthritis Pain, Annual Cost of Therapy ($’000), 2006–2012 82 

 Table 40: Pain Management Therapeutics Market, Top Seven Markets, Rheumatoid Arthritis Pain, Annual Cost of Therapy Forecast ($’000), 2012–2019 82 

 Table 41: Pain Management Therapeutics Market, Top Seven Markets, Rheumatoid Arthritis Pain, Treatment Usage Pattern (million), 2006–2012 84 

 Table 42: Pain Management Therapeutics Market, Top Seven Markets, Rheumatoid Arthritis Pain, Treatment Usage Pattern Forecast (million), 2012–2019 84 

 Table 43: Pain Management Therapeutics Market, Top Seven Markets, Low Back Pain, Revenue ($bn), 2006–2012 89 

 Table 44: Pain Management Therapeutics Market, Top Seven Markets, Low Back Pain, Revenue Forecast ($bn), 2012–2019 89 

 Table 45: Pain Management Therapeutics Market, Top Seven Markets, Low Back Pain, Annual Cost of Therapy ($), 2006–2012 90 

 Table 46: Pain Management Therapeutics Market, Top Seven Markets, Low Back Pain, Annual Cost of Therapy Forecast ($), 2012–2019 90 

 Table 47: Pain Management Therapeutics Market, Top Seven Markets, Low Back Pain, Treatment Usage Pattern (million), 2006–2012 92 

 Table 48: Pain Management Therapeutics Market, Top Seven Markets, Low Back Pain, Treatment Usage Pattern Forecast (million), 2012–2019 93 

 Table 49: Pain Management Therapeutics Market, Top Seven Markets, Post-operative Pain, Revenue ($bn), 2006–2012 97 

 Table 50: Pain Management Therapeutics Market, Top Seven Markets, Post-operative Pain, Revenue Forecast ($bn), 2012–2019 97 

 Table 51: Pain Management Therapeutics Market, Top Seven Markets, Post-operative Pain, Annual Cost of Therapy ($), 2006–2012 98 

 Table 52: Pain Management Therapeutics Market, Top Seven Markets, Post-operative Pain, Annual Cost of Therapy Forecast ($), 2012–2019 98 

 Table 53: Pain Management Therapeutics Market, Top Seven Markets, Post-operative Pain, Treatment Usage Pattern Forecast (million), 2006–2012 100 

 Table 54: Pain Management Therapeutics Market, Top Seven Markets, Post-operative Pain, Treatment Usage Pattern Forecast (million), 2012–2019 100 

 Table 55: Pain Management Therapeutics Market, US, Revenue ($bn), 2006–2012 105 

 Table 56: Pain Management Therapeutics Market, US, Revenue Forecast ($bn), 2012–2019 105 

 Table 57: Pain Management Therapeutics Market, US, Annual Cost of Therapy ($), 2006–2012 106 

 Table 58: Pain Management Therapeutics Market, US, Annual Cost of Therapy Forecast ($), 2012–2019 106 

 Table 59: Pain Management Therapeutics Market, US, Treatment Usage Pattern (million), 2006–2012 107 

 Table 60: Pain Management Therapeutics Market, US, Treatment Usage Pattern Forecast (million), 2012–2019 107 

 Table 61: Pain Management Therapeutics Market, Top Five European Countries, Revenue ($bn), 2006–2012 109 

 Table 62: Pain Management Therapeutics Market, Top Five European Countries, Revenue Forecast ($bn), 2012–2019 109 

 Table 63: Pain Management Therapeutics Market, Top Five European Countries, Annual Cost of Therapy ($), 2006–2012 110 

 Table 64: Pain Management Therapeutics Market, Top Five European Countries, Annual Cost of Therapy Forecast ($), 2012–2019 110 

 Table 65: Pain Management Therapeutics Market, Top Five European Countries, Treatment Usage Pattern (million), 2006–2012 111 

 Table 66: Pain Management Therapeutics Market, Top Five European Countries, Treatment Usage Pattern Forecast (million), 2012–2019 111 

 Table 67: Pain Management Therapeutics Market, Japan, Revenue ($bn), 2006–2019 113 

 Table 68: Pain Management Therapeutics Market, Japan, Revenue Forecast ($bn), 2006–2019 113 

 Table 69: Pain Management Therapeutics Market, Japan, Annual Cost of Therapy ($), 2006–2012 114 

 Table 70: Pain Management Therapeutics Market, Japan, Annual Cost of Therapy Forecast ($), 2012–2019 114 

 Table 71: Pain Management Therapeutics Market, Japan, Treatment Usage Pattern (million), 2006–2012 115 

 Table 72: Pain Management Therapeutics Market, Japan, Treatment Usage Pattern Forecast (million), 2012–2019 115 

 Table 73: Pain Management Therapeutics Market, India, Marketed Products, 2013 120 

 Table 74: Cipla, India, Marketed Products, 2013 121 

 Table 75: Sun Pharmaceuticals, India, Marketed Products, 2013 122 

 Table 76: Zydus Cadila, India, Marketed Products, 2013 123 

 Table 77: Lupin, India, Marketed Products, 2013 124 

 Table 78: Pain Management Therapeutics Market, China, Marketed Products, 2013 128 

 Table 79: Pain Management Therapeutics Market, China, Xian Janssen Marketed Products, 2013 128 

 Table 80: Xian Janssen, China, Marketed Products, 2013 129 

 Table 81: Pain Management Therapeutics Market, Australia, Marketed Products, 2013 130 

 Table 82: Alphapharm, Australia, Marketed Products, 2013 131 

 Table 83: Apotex, Australia, Marketed Products, 2013 132 

 Table 84: Aspen, Australia, Marketed Products, 2013 133 

 Table 85: Pain Management Therapeutics Market, Global, Fibromyalgia R&D Pipeline by Phase (%), 2013 137 

 Table 86: Pain Management Therapeutics Market, Global, Neuropathic Pain R&D Pipeline by Phase, 2013 139 

 Table 87: Pain Management Therapeutics Market, Global, Migraine R&D Pipeline by Phase (%), 2013 144 

 Table 88: Pain Management Therapeutics Market, Global, Cancer Pain R&D Pipeline by Phase, 2013 147 

 Table 89: Pain Management Therapeutics Market, Global, Osteoarthritis Pain R&D Pipeline by Phase (%), 2013 149 

 Table 90: Pain Management Therapeutics Market, Global, Low Back Pain R&D Pipeline by Phase, 2013 151 

 Table 91: Pain Management Therapeutics Market, Global, Post-operative Pain R&D Pipeline by Phase, 2013 153 

 Table 92: Pain Management Therapeutics Market, Global, Recent M&A Deals, 2011–2013 170 

 Table 93: Pain Management Therapeutics Market, Global, Recent Licensing Agreements, 2011–2013 174 

 Table 94: Pain Management Therapeutics Market, Global, Recent Partnership Deals, 2011–2013 177 

  

 1.2 List of Figures 

 Figure 1: Pain Management Therapeutics Market, Top Seven Markets, Revenue by Indication (%), 2012 17 

 Figure 2: Pain Management Therapeutics Market, WHO Three-Step Ladder for Pain Management, 2013 18 

 Figure 3: Pain Management Therapeutics Market, Opioids – Adverse Effects, 2013 19 

 Figure 4: Pain Management Therapeutics Market, Top Seven Markets, Revenue Forecast ($bn), 2006–2019 20 

 Figure 5: Pain Management Therapeutics Market, Top Seven Markets, Annual Cost of Therapy Forecast ($), 2006–2019 32 

 Figure 6: Pain Management Therapeutics Market, Top Seven Markets, Treatment Usage Pattern Forecast (million), 2006–2019 33 

 Figure 7: Pain Management Therapeutics Market, Drivers and Restraints, 2013 35 

 Figure 8: Pain Management Therapeutics Market, Top Seven Markets, Fibromyalgia, Revenue Forecast ($bn), 2006–2019 37 

 Figure 9: Pain Management Therapeutics Market, Top Seven Markets, Fibromyalgia, Annual Cost of Therapy Forecast ($), 2006–2019 39 

 Figure 10: Pain Management Therapeutics Market, Global, Fibromyalgia, Treatment Algorithm, 2013 40 

 Figure 11: Pain Management Therapeutics Market, Top Seven Markets, Fibromyalgia, Treatment Usage Pattern Forecast (million), 2006–2019 41 

 Figure 12: Pain Management Therapeutics Market, Top Seven Markets, Fibromyalgia, Segmentation by Geography (%), 2012 43 

 Figure 13: Pain Management Therapeutics Market, Fibromyalgia, Drivers and Restraints, 2013 44 

 Figure 14: Pain Management Therapeutics Market, Top Seven Markets, Neuropathic Pain, Revenue Forecast ($bn), 2006–2019 46 

 Figure 15: Pain Management Therapeutics Market, Top Seven Markets, Neuropathic Pain, Annual Cost of Therapy Forecast ($), 2006–2019 48 

 Figure 16: Pain Management Therapeutics Market, Global, Neuropathic Pain Treatment Algorithm 49 

 Figure 17: Pain Management Therapeutics Market, Top Seven Markets, Neuropathic Pain, Treatment Usage Pattern Forecast (million), 2006–2019 50 

 Figure 18: Pain Management Therapeutics Market, Top Seven Markets, Neuropathic Pain, Segmentation by Geography (%), 2012 52 

 Figure 19: Pain Management Therapeutics Market, Global, Neuropathic Pain Drivers and Restraints, 2013 53 

 Figure 20: Pain Management Therapeutics Market, Top Seven Markets, Migraine, Revenue Forecast ($bn), 2006–2019 55 

 Figure 21: Pain Management Therapeutics Market, Top Seven Markets, Migraine, Annual Cost of Therapy Forecast ($), 2006–2019 57 

 Figure 22: Pain Management Therapeutics Market, Global, Migraine, Treatment Algorithm 58 

 Figure 23: Pain Management Therapeutics Market, Top Seven Markets, Migraine, Treatment Usage Pattern Forecast (million), 2006–2019 59 

 Figure 24: Pain Management Therapeutics Market, Top Seven Markets, Migraine, Segmentation by Geography (%), 2012 61 

 Figure 25: Pain Management Therapeutics Market, Migraine, Drivers and Restraints, 2013 62 

 Figure 26: Pain Management Therapeutics Market, Top Seven Markets, Cancer Pain, Revenue Forecast ($bn), 2006–2019 64 

 Figure 27: Pain Management Therapeutics Market, Top Seven Markets, Cancer Pain, Annual Cost of Therapy Forecast ($), 2006–2019 65 

 Figure 28: Pain Management Therapeutics Market, Global, Cancer Pain, Treatment Algorithm 66 

 Figure 29: Pain Management Therapeutics Market, Top Seven Markets, Cancer Pain, Treatment Usage Pattern Forecast (million), 2006–2019 67 

 Figure 30: Pain Management Therapeutics Market, Top Seven Markets, Cancer Pain, Segmentation by Geography (%), 2012 69 

 Figure 31: Pain Management Therapeutics Market, Global, Cancer Pain, Drivers and Restraints, 2013 70 

 Figure 32: Pain Management Therapeutics Market, Top Seven Markets, Osteoarthritis Pain, Revenue Forecast ($bn), 2006–2019 72 

 Figure 33: Pain Management Therapeutics Market, Top Seven Markets, Osteoarthritis Pain, Annual Cost of Therapy Forecast ($), 2006–2019 74 

 Figure 34: Pain Management Therapeutics Market, Global, Osteoarthritis Pain Treatment Algorithm 75 

 Figure 35: Pain Management Therapeutics Market, Top Seven Markets, Osteoarthritis Pain, Treatment Usage Pattern Forecast (million), 2006–2019 76 

 Figure 36: Pain Management Therapeutics Market, Top Seven Markets, Osteoarthritis Pain, Segmentation by Geography (%), 2012 78 

 Figure 37: Pain Management Therapeutics Market, Global, Osteoarthritis Pain, Drivers and Restraints, 2013 79 

 Figure 38: Pain Management Therapeutics Market, Top Seven Markets, Rheumatoid Arthritis Pain, Revenue Forecast ($bn), 2006–2019 80 

 Figure 39: Pain Management Therapeutics Market, Top Seven Markets, Rheumatoid Arthritis Pain, Annual Cost of Therapy Forecast ($’000), 2006–2019 82 

 Figure 40: Pain Management Therapeutics Market, Global, Rheumatoid Arthritis Pain, Treatment Algorithm 83 

 Figure 41: Pain Management Therapeutics Market, Top Seven Markets, Rheumatoid Arthritis Pain, Treatment Usage Pattern Forecast (million), 2006–2019 84 

 Figure 42: Pain Management Therapeutics Market, Top Seven Markets, Rheumatoid Arthritis Pain, Segmentation by Geography (%), 2012 86 

 Figure 43: Pain Management Therapeutics Market, Global, Rheumatoid Arthritis Pain Drivers and Restraints, 2013 87 

 Figure 44: Pain Management Therapeutics Market, Top Seven Markets, Low Back Pain, Revenue Forecast ($bn), 2006–2019 88 

 Figure 45: Pain Management Therapeutics Market, Top Seven Markets, Low Back Pain, Annual Cost of Therapy Forecast ($), 2006–2019 90 

 Figure 46: Pain Management Therapeutics Market, Global, Low Back Pain, Treatment Algorithm 91 

 Figure 47: Pain Management Therapeutics Market, Top Seven Markets, Low Back Pain, Treatment Usage Pattern Forecast (million), 2006–2019 92 

 Figure 48: Pain Management Therapeutics Market, Top Seven Markets, Low Back Pain, Segmentation by Geography (%), 2012 94 

 Figure 49: Pain Management Therapeutics Market, Global, Low Back Pain Drivers and Restraints, 2013 95 

 Figure 50: Pain Management Therapeutics Market, WFSA Three-step Ladder for Pain Management 96 

 Figure 51: Pain Management Therapeutics Market, Top Seven Markets, Post-operative Pain, Revenue Forecast ($bn), 2006–2019 97 

 Figure 52: Pain Management Therapeutics Market, Top Seven Markets, Post-operative Pain, Annual Cost of Therapy Forecast ($), 2006–2019 98 

 Figure 53: Pain Management Therapeutics Market, Global, Post-operative Pain Treatment Algorithm 99 

 Figure 54: Pain Management Therapeutics Market, Top Seven Markets, Post-operative Pain, Treatment Usage Pattern Forecast (million), 2006–2019 100 

 Figure 55: Pain Management Therapeutics Market, Top Seven Markets, Post-operative Pain, Segmentation by Geography (%), 2012 102 

 Figure 56: Pain Management Therapeutics Market, Global, Post-operative Pain Drivers and Restraints, 2013 103 

 Figure 57: Pain Management Therapeutics Market, Top Seven Markets, Market Share by Geography (%), 2012 104 

 Figure 58: Pain Management Therapeutics Market, US, Revenue Forecast ($bn), 2006–2019 105 

 Figure 59: Pain Management Therapeutics Market, US, Annual Cost of Therapy Forecast ($), 2006–2019 106 

 Figure 60: Pain Management Therapeutics Market, US, Treatment Usage Pattern Forecast (million), 2006–2019 107 

 Figure 61: Pain Management Therapeutics Market, Top Five European Countries, Revenue Forecast ($bn), 2006–2019 109 

 Figure 62: Pain Management Therapeutics Market, Top Five European Countries, Annual Cost of Therapy Forecast ($), 2006–2019 110 

 Figure 63: Pain Management Therapeutics Market, Top Five European Countries, Treatment Usage Pattern Forecast (million), 2006–2019 111 

 Figure 64: Pain Management Therapeutics Market, Japan, Revenue Forecast ($bn), 2006–2019 113 

 Figure 65: Pain Management Therapeutics Market, Japan, Annual Cost of Therapy Forecast ($), 2006–2019 114 

 Figure 66: Pain Management Therapeutics Market, Japan, Treatment Usage Pattern Forecast (million), 2006–2019 115 

 Figure 67: Pain Management Therapeutics Market, India, Intellectual Property Rights Protection Framework, 2011 117 

 Figure 68: Pain Management Therapeutics Market, India, Regulatory Landscape, Intellectual Property Rights Protection, 1963–2005 118 

 Figure 69: Pain Management Therapeutics Market, Global, R&D Pipeline by Indication (%), 2013 134 

 Figure 70: Pain Management Therapeutics Market, Global, R&D Pipeline by Phase (%), 2013 135 

 Figure 71: Pain Management Therapeutics Market, Global, Fibromyalgia R&D Pipeline by Phase (%), 2013 136 

 Figure 72: Pain Management Therapeutics Market, Global, Neuropathic Pain R&D Pipeline by Phase (%), 2013 138 

 Figure 73: Pain Management Therapeutics Market, Global, Migraine R&D Pipeline by Phase (%), 2013 143 

 Figure 74: Pain Management Therapeutics Market, Global, Cancer Pain R&D Pipeline by Phase (%), 2013 146 

 Figure 75: Pain Management Therapeutics Market, Global, Osteoarthritis Pain R&D Pipeline by Phase (%), 2013 148 

 Figure 76: Pain Management Therapeutics Market, Global, Low Back Pain R&D Pipeline by Phase (%), 2013 150 

 Figure 77: Pain Management Therapeutics Market, Global, Post-operative Pain R&D Pipeline by Phase (%), 2013 152 

 Figure 78: Pain Management Therapeutics Market, Global, Number of M&A Deals by Year, 2007–2013 168 

 Figure 79: Pain Management Therapeutics Market, Global, M&A Deals by Indication (%),2007–2013 169 

 Figure 80: Pain Management Therapeutics Market, Global, Number of Licensing Deals by Year, 2007–2013 171 

 Figure 81: Pain Management Therapeutics Market, Global, Licensing Agreements by Indication (%), 2007–2013 172 

 Figure 82: Pain Management Therapeutics Market, Global, Licensing Agreements by Phase (%), 2007–2013 173 

 Figure 83: Pain Management Therapeutics Market, Global, Number of Partnership Deals by Year, 2007–2013 175 

 Figure 84: Pain Management Therapeutics Market, Global, Co-Development Deals by Indication (%), 2007–2013 176 

 Figure 85: GBI Research Market Forecasting Model 185