US Cancer Diagnostics Market 2014 - Sales Forecasts, Supplier Shares, Competitive Strategies




Published: January 2014 | Pages: 620 | Format: PDF

 "US Cancer Diagnostics Market 2014: Sales Forecasts, Supplier Shares, Competitive Strategies" is a new strategic analysis of the major business opportunities emerging in the cancer diagnostics market during the next five years. The report examines trends in the US cancer diagnostics markets; reviews current and emerging tests; analyzes potential applications of various diagnostic technologies; forecasts sales of major tumor markers and market segment; profiles leading market players and potential entrants; and suggests alternative business expansion strategies for suppliers. 

 Rationale 

 The cancer diagnostics market is on the verge of explosion, as the researchers approach major technological breakthroughs in tumor diagnosis and therapy, discover new specific antigens, and unlock the mystery of the genetic basis of the disease. During the next five years, the worldwide cancer diagnostics market is promising to be an exciting, dynamic and rapidly expanding field. Anticipated technological breakthroughs will create numerous opportunities for determining genetic predisposition, detecting specific tumors, and monitoring biological response to cancer therapy. The rise in geriatric population will further compound the growing demand for malignancy assays and the rapid market expansion. 

 Business Opportunities and Strategic Recommendations 

 - Specific new product development opportunities with potentially significant market appeal during the next five years. 

 - Design criteria for new products. 

 - Alternative market penetration strategies. 

 - Potential market entry barriers and risks. 

 Cancer Diagnostic Tests—Over 200 current and emerging assays including: 

 ACTH, AFP, Beta-2 Microglobulin, CA 15-3/27.29, CA 19-9, CA 125, Calcitonin, Cathepsin, CEA, Chromogranin, Colon-Specific Antigen, Cytokeratins, Estrogen Receptor, Ferritin, Gastrin, HCG, Insulin, Interferons, Interleukins, Lymphocyte Subtyping, Neuron-Specific Enolase, Nucleolar, Occult Blood, Oncogenes, Pancreatic Oncofetal Antigen, Pap Smear, Parathyroid Hormone, Progesterone Receptor, Prostatic Acid Phosphatase, Prostatic Specific Antigen, S-100 Protein, Serotonin, Sialic Acid, Squamous Cell Carcinoma Ag, TDT, Thymidine Kinase, Thyroglobulin, Tissue Polypeptide Antigen, and others. 

 Market Segmentation Analysis 

 - Sales and market shares of major suppliers, by individual cancer diagnostic test. 

 - Five-year test volume and sales forecasts for major cancer diagnostic tests by market segment, including: 

 - Hospitals 

 - Commercial/Private Laboratories 

 - Physician Offices/Group Practices 

 - Cancer Clinics 

 - Comprehensive market segmentation analysis, including review of the market dynamics, structure, size, growth and major suppliers. 

 - Cancer statistics, etiology and recent developments. 

 Current and Emerging Products 

 - Review of over 200 current and emerging cancer diagnostic tests, including: 

 - Biochemical Markers 

 - Oncogenes 

 - Growth Factors 

 - Hormones 

 - Colony Stimulating Factors 

 - Lymphokines 

 - Immunohistochemical Stains, and others. 

 - Analysis of major immunoassay analyzers used for cancer diagnostic testing, including their operating characteristics, features and selling prices. 

 Technology Review 

 - Assessment of monoclonal antibodies, immunoassays, DNA probes, biochips/microarrays, chromosome analysis, IT, artificial intelligence, flow cytometry, biosensors, and other technologies and their potential applications for cancer diagnostic testing. 

 - Review of competing/complementing technologies, including CT, MRI, NMR, PET and photonics spectroscopy. 

 - Extensive listings of over 500 companies, universities and research centers developing new cancer diagnostic tests and detection technologies. 

 Competitive Assessments 

 - Strategic assessments of major suppliers and start-up firms developing innovative technologies and products, including their sales, product portfolios, marketing tactics, collaborative arrangements, and new products in R&D. 

 Contains 620 pages and 103 tables 

 I. Introduction 

 II. Worldwide Market and Technology Overview 

 A. Cancer Statistics and Etiology 

 1. Breast Cancer 

 2. Lung Cancer 

 3. Colon and Rectum Cancer 

 4. Prostate Cancer 

 5. Stomach Cancer 

 6. Leukemia 

 7. Lymphoma 

 8. Oral Cancer 

 9. Skin Cancer 

 10. Uterine Cancer 

 11. Ovarian Cancer 

 12. Bladder Cancer 

 B. Major Current And Emerging Cancer Diagnostic Tests 

 1. Introduction 

 2. Tumor Marker Classification 

 3. ACTH 

 4. Alpha-Fetoprotein (AFP) 

 5. Beta-2 Microglobulin 

 6. CA 15-3/27.29 

 7. CA 19-9 

 8. CA-125 

 9. Calcitonin 

 10. Carcinoembrionic Antigen (CEA) 

 11. Estrogen and Progesterone Receptors 

 12. Ferritin 

 13. Gastrin 

 14. Human Chorionic Gonadotropin (HCG) 

 15. Insulin 

 16. NSE 

 17. Occult Blood 

 18. PAP Smear/HPV 

 19. Prostatic Acid Phosphatase (PAP) 

 20. Prostate-Specific Antigen (PSA) 

 21. Squamous Cell Carcinoma Antigen (SCC) 

 22. T and B Lymphocytes 

 23. TdT 

 24. Thyroglobulin 

 25. Tissue Polypeptide Antigen (TPA) 

 26. Biochemical Tumor Markers 

 - ADA 

 - B-Protein 

 - PNP 

 - 5'-Nucleotidase  

 27. Oncogenes 

 - Abl/abl-bcr 

 - AIB1 

 - BCL-2 

 - BRCA1 

 - CD44 

 - C-fos 

 - C-myb 

 - C-myc 

 - CYP-17 

 - Erb-B 

 - HPC1 

 - N-myc 

 - P40 

 - P51 

 - P53 

 - PIK3CA 

 - PTI-1 

 - Ras 

 - Reg 

 - Sis 

 - Src 

  

 28. Polypeptide Growth Factors 

 - Basic Fibroblast Growth Factor 

 - Beta-TGF 

 - Cachectin (TNT) 

 - Calmodulin 

 - ECFR 

 - Nerve Growth Factor (NGF) 

 - Epidermal Growth Factor (EGF) 

 - Ornithine Decarboxylase 

 - Transferrin 

 - Transforming Growth Factor-Alpha  

 29. Ectopic Hormones 

 30. Colony Stimulating Factors 

 31. Lymphokines 

 - Alpha-Interferon 

 - B Cell Growth Factors 

 - B Cell Growth Factor (BCGF) 

 - Gamma-Interferon 

 - Interleukin-1 (IL-1) 

 - Macrophage Activating Factor 

 32. Immunohistochemical Stains 

 33. Emerging Tumor Markers 

 - N-Acetylglucosamine 

 - Actin 

 - Alpha-Actin 

 - Antineuronal Antibodies 

 - 7B2 

 - B72.3 

 - Bax 

 - BCD-F9 

 - BLCA-4 

 - Blood Group Antigens A,B,H 

 - CA 50 

 - CA 72-4/TAG-72 

 - CA 195 

 - CA-242 

 - CA-549 

 - CAM 26 

 - CAR-3 

 - Cathepsin-D 

 - Chromogranin A and B 

 - Cluster 1 Antigen 

 - Cluster-5/5A Antigen 

 - CTA 

 - CU18 

 - DR-70 

 - DU-PAN-2 

 - Endometrial Bleeding Associated Factor 

 - Endostatin 

 - Epithelial Membrane Antigen 

 - Feulgen Hydrolysis 

 - Fibronectin 

 - FSH 

 - (1->3)-L-fucosyltransferase 

 - Gastrin-Releasing Peptide (GRP) 

 - GDCFP-15 

 - Glucagon 

 - Glycoamines 

 - H23 

 - Her-2 

 - Human Carcinoma Antigen 

 - HPA 

 - HSP27 

 - Intermediate Filaments 

 - Cytokeratins/CK18/Cyfra 21-1 

 - Desmin 

 - Gliofibrillary Acid Protein 

 - Neurofilaments 

 - Vimentin 

 - KA 93 

 - Kinases 

 - KP16D3 

 - LAI 

 - Leukocyte Common Antigen 

 - Lewis Antigens 

 - Lysophosphatidic Acid (LPA) 

 - Ma 695/Ma 552 

 - MABDF3 

 - MAG 

 - ME1 

 - Minactivin 

 - MN/CA9 

 - MSA 

 - Mucin Cancer Antigen (MCA) 

 - Multiple Tumor Suppressor 1 

 - Myosin 

 - NEA-130 

 - NMP22 

 - OA-519 

 - Opiod Peptides 

 - P-glycoprotein 

 - Pancreatic Oncofetal Antigen (POA) 

 - Placental Lactogen 

 - PR92 

 - Proliferative Index, Ki-67 

 - Px 

 - RB Inactivation/Deletion 

 - Ret 

 - SCCL 175 

 - Selectin 

 - Sialic Acid 

 - Sialyl SSEA-1/SLX 

 - SN10 

 - Somatostatin 

 - TA-90 

 - TABA 

 - Tachykinin 

 - TAG 12 

 - TPS 

 - Troponin 

 - Tubulin 

 - VCAM 

 - VEGF 

 - Villen 

 C. Instrumentation Review And Market Needs 

 D. Current and Emerging Technologies 

 1. Monoclonal and Polyclonal Antibodies 

 2. Immunoassays 

 a. Technological Principle 

 b. Radioimmunoassay (RIA) 

 c. Enzyme Immunoassays (EIA) 

 - Overview 

 - ELISA 

 - Immunofiltration 

 - Particle-Membrane Capture Immunoassay 

 - Enzyme Amplification 

 d. Fluorescent Immunoassays 

 e. Luminescence 

 - Chemiluminescence 

 - Bioluminescence 

 f. Latex Agglutination 

 g. Immunoprecipitation 

 h. Affinity Chromatographu 

 e. Liposome Flow-Injection Immunoassay 

 3. Molecular Diagnostics 

 a. Technology Overview 

 b. Amplification Methods 

 4. Chromosome Analysis 

 a. Chronic Myelogenous Leukemia (CML) 

 b. Acute Myeloid Leukemia (AML) 

 c. Acute Lymphoblastic Leukemia (ALL) 

 d. Malignant Lymphomas Lymphoid Malignancies 

 e. Chronic Lymphocytic Leukemia (CLL) 

 f. Solid Cancers 

 g. Chromosomal Translocation and Oncogenes 

 5. Artificial Intelligence 

 6. Flow Cytometry 

 7. Two Dimensional Gel Electrophoresis (2-DGE) 

 8. Biosensors 

 9. Competing/Complementing Technologies 

 a. CT 

 b. MRI 

 c. NMR 

 d. PET 

 e. Photonics Spectroscopy 

 G. Personal Testing 

 III. U.S.A. 

 A. Executive Summary 

 B. Business Environment 

 C. Market Structure 

 D. Market Size, Growth and Major Suppliers Sales 

 and Market Shares 

 X. Major Product Development Opportunities 

 A. Reagent Kits and Test Systems/Panels 

 B. Instrumentation 

 C. Computers, Software and Automation 

 D. Auxiliary Products 

 XI. Design Criteria for Decentralized Testing Products 

 XII. Alternative Market Penetration Strategies 

 A. Internal Development 

 B. Collaborative Arrangements 

 C. University Contracts 

 D. Distribution Strategies 

 1. Marketing Approaches 

 2. Product Complexity  

 3. Customer Preference  

 4. Established Suppliers 

 5. Emerging Suppliers 

 6. Major Types of Distributors 

 7. Market Segmentation Factor 

 XIII. Potential Market Entry Barriers and Risks 

 A. Market Maturity 

 B. Cost Containment 

 C. Competition 

 D. Technological Edge and Limitations 

 E. Patent Protection 

 F. Regulatory Constraints 

 G. Decentralized Testing Market Challenges 

 XIV. Competitive Profiles 

 - Abbott 

 - AdnaGen 

 - Agilent Technologies 

 - Applied Gene Technologies 

 - Arca/Nuvelo 

 - Beckman Coulter/Danaher 

 - Becton Dickinson 

 - Biomedical Diagnostics 

 - bioMerieux 

 - Bio-Rad 

 - CellSearch 

 - Cepheid 

 - Correlogic Systems/Vermillion 

 - Decode 

 - Diadexus 

 - Diagnocure 

 - Diasorin 

 - Eiken Chemical 

 - Epigenomics 

 - Enterix 

 - Enzo Biochem 

 - Exact Sciences 

 - Fujirebio/Innogenetics 

 - Guided Therapeutics 

 - Hologic/Gen-Probe 

 - Kreatech 

 - Kyowa Medex 

 - Life Technologies 

 - Mackay Life Sciences 

 - Myriad Genetics 

 - Nanogen Elitech 

 - OncoLab 

 - Ortho-Clinical Diagnostics 

 - Panacea Pharmaceuticals 

 - Polartechnics 

 - Polymedco 

 - PreMD 

 - Qiagen/Ipsogen 

 - Quest Diagnostics 

 - Radient Pharmaceuticals 

 - Roche 

 - Scienion 

 - Sequenom 

 - Siemens Healthcare 

 - Takara Bio 

 - Targeted Diagnostics & Therapeutics 

 - Tosoh  

 - Veridex 

 - Wako Pure Chemicals 

 - Wallac/PE 

 - Zila  

  

 XV. Appendixes: Appendix I: Major Universities and Research 

 Centers Developing Cancer Diagnostic 

 Technology and Applications 

 Appendix II: Assumed Currency Exchange Rates 

  

 List of Tables 

 Tumor Marker Classification 

 Major Companies Developing or Marketing 

 ACTH Tests 

 Major Companies Developing or Marketing 

 AFP Tests 

 Major Companies Developing or Marketing 

 Beta-2 Microglobulin Tests 

 Major Companies Developing or Marketing 

 CA 15-3/27.29 Tests 

 Major Companies Developing or Marketing 

 CA 19-9 Tests 

 Major Companies Developing or Marketing 

 CA 125 Tests 

 Major Companies Developing or Marketing 

 Calcitonin Tests 

 Major Companies Developing or Marketing 

 CEA Tests 

 Major Companies Developing or Marketing 

 Estrogen Receptor Tests 

 Major Companies Developing or Marketing 

 Progesterone Receptor Tests 

 Major Companies Developing or Marketing 

 Ferritin Tests 

 Major Companies Developing or Marketing 

 Gastrin Tests 

 Major Companies Developing or Marketing 

 HCG Tests  

  

 Major Companies Developing or Marketing 

 Insulin Tests 

  

 Major Companies Developing or Marketing 

 NSE Tests 

 Major Companies Developing or Marketing 

 Occult Blood Tests 

 Major Companies Developing or Marketing 

 PAP Smear/HPV Tests 

 Major Companies Developing or Marketing 

 PAP Tests 

 Major Companies Developing or Marketing 

 PSA Tests 

 Major Companies Developing or Marketing 

 Lymphocyte Subclassification Tests 

 Biochemical Markers Potential Applications  

 In Cancer Diagnosis 

 Oncogenes Potential Applications  

 In Cancer Diagnosis 

 Major Companies Developing or Marketing 

 Oncogene Tests 

 Growth Factors Potential Applications  

 In Cancer Diagnosis 

 Colony Stimulating Factors Potential  

 Applications in Cancer Diagnosis 

 Lymphokines Potential Applications In Cancer Diagnosis 

 Immunohistochemical Stains Potential 

 Applications in Cancer Diagnosis 

 Executive Summary Table: U.S., Total Tumor  

 Marker Test Volume and Sales Forecast 

 By Market Segment  

 U.S., Estimated New Cancer Cases and Deaths 

  

 U.S., Estimated Cancer Death Rates 

 Per 100,000 Population 

 U.S., Laboratories Performing Tumor 

 Marker Tests by Market Segment 

 U.S., Hospital Laboratories Performing 

 Tumor Marker Tests by Bed Size 

 U.S., Commercial/Private Laboratories 

 Performing Tumor Marker Tests  

 By Annual Test Volume 

 U.S., Physician Office Laboratories 

 Performing Tumor Marker Tests 

 By Practice Size 

 U.S., Total Tumor Marker Test Volume  

 Forecast by Market Segment 

  

 U.S., All Market Segments Major  

 Tumor Marker Test Volume Forecast  

 U.S., Hospital Laboratories Major Tumor 

 Marker Test Volume Forecast by Test  

 U.S., Commercial/Private Laboratories 

 Major Tumor Marker Test Volume Forecast  

 U.S., Physician Offices/Group Practices 

 Major Tumor Marker Test Volume Forecast  

 U.S., Cancer Clinics Major Tumor 

 Marker Test Volume Forecast by Test  

 U.S., Total Tumor Marker Sales 

 Forecast by Market Segment  

 U.S., All Market Segment Major Tumor 

 Marker Sales Forecast by Test  

 U.S., Hospital Laboratories Major Tumor 

 Marker Sales Forecast by Test  

 U.S., Commercial/Private Laboratories 

 Major Tumor Marker Sales Forecast by Test  

 U.S., Physician Offices/Group Practices 

 Major Tumor Marker Sales Forecast by Test  

 U.S., Cancer Clinics Major Tumor 

 Marker Sales Forecast by Test  

 U.S., ACTH Test Volume and Diagnostics 

 Sales Forecast by Market Segment 

  

 U.S., AFP Test Volume and Diagnostics 

 Sales Forecast by Market Segment  

 U.S., Beta-2 Microglobulin Test Volume and 

 Diagnostics Sales Forecast by Market Segment  

 U.S., CA 15-3/27.29 Test Volume and  

 Diagnostics Sales Forecast by Market Segment  

 U.S., CA 19-9 Test Volume and Diagnostics 

 Sales Forecast by Market Segment  

 U.S., CA-125 Test Volume and Diagnostics 

 Sales Forecast by Market Segment  

 U.S., Calcitonin Test Volume and  

 Diagnostics Sales Forecast by Market Segment  

 U.S., Cathepsin Test Volume and Diagnostics 

 Sales Forecast by Market Segment  

 U.S., CEA Test Volume and Diagnostics  

 Sales by Market Segment 

 U.S., Chromogranin Test Volume and  

 Diagnostics Sales Forecast by Market Segment  

 U.S., Colon-specific Antigen Test Volume 

 And Diagnostics Sales Forecast by Market Segment  

 U.S., Cytokeratins Test Volume 

 And Diagnostics Sales Forecast by Market Segment  

 U.S., Estrogen Receptor Test Volume  

 And Diagnostics Sales Forecast by Market Segment 

  

 U.S., Ferritin Test Volume and Diagnostics 

 Sales Forecast by Market Segment  

 U.S., Gastrin Test Volume and Diagnostics 

 Sales Forecast by Market Segment  

 U.S., HCG Test Volume and Diagnostics  

 Sales Forecast by Market Segment  

 U.S., Insulin Test Volume and Diagnostics 

 Sales Forecast by Market Segment  

 U.S., Interferons Test Volume 

 And Diagnostics Sales Forecast by Market  

 Segment  

 U.S., Interleukins Test Volume 

 And Diagnostics Sales Forecast  

 by Market Segment 

  

 U.S., Lymphocyte Subtyping Test Volume and  

 Diagnostics Sales Forecast by Market Segment  

 U.S., NSE Test Volume and Diagnostics 

 Sales Forecast by Market Segment  

 U.S., Nucleolar Test Volume and Diagnostics 

 Sales Forecast by Market Segment  

 U.S., Occult Blood Test Volume 

 And Diagnostics Sales Forecast by Market Segment  

 U.S., Oncogenes Test Volume and Diagnostics 

 Sales Forecast by Market Segment  

 U.S., Pancreatic Oncofetal Antigen 

 Test Volume and Diagnostics  

 Sales Forecast by Market Segment  

 U.S., PAP Smear Test Volume and Diagnostics  

 Sales Forecast by Market Segment  

 U.S., Parathyroid Hormone  

 Test Volume and Diagnostics  

 Sales Forecast by Market Segment  

 U.S., Progesterone Receptor 

 Test Volume and Diagnostics  

 Sales Forecast by Market Segment  

 U.S., PAP Test Volume and Diagnostics 

 Sales Forecast by Market Segment  

 U.S., PSA Test Volume and Diagnostics  

 Sales Forecast by Market Segment  

 U.S., S-100 Protein Test Volume and  

 Diagnostics Sales Forecast by Market  

 Segment  

 U.S., Serotonin Test Volume and Diagnostics 

 Sales Forecast by Market Segment  

 U.S., Sialic Acid Test Volume and Diagnostics 

 Sales Forecast by Market Segment  

 U.S., Squamous Cell Carcinoma Antigen 

 Test Volume and Diagnostics  

 Sales Forecast by Market Segment  

 U.S., TDT Test Volume and Diagnostics  

 Sales Forecast by Market Segment  

 U.S., Thymidine Kinase  

 Test Volume and Diagnostics  

 Sales Forecast by Market Segment  

 U.S., Thyroglobulin Test 

 Volume and Diagnostics  

 Sales Forecast by Market Segment  

 U.S., TPA Test Volume and Diagnostics 

 Sales Forecast by Market Segment  

 U.S., Total Tumor Marker Sales  

 By Major Supplier 

 U.S., ACTH Testing Market Diagnostics  

 Sales by Major Supplier 

 U.S., AFP Testing Market Diagnostics  

 Sales by Major Supplier 

 U.S., Beta-2 Migroblolulin Testing Market Diagnostics Sales  

 by Major Supplier 

 U.S., CA 15-3/27.29 Testing Market  

 Diagnostics Sales by Major Supplier 

 U.S., CA 19-9 Testing Market Diagnostics  

 Sales by Major Supplier 

 U.S., CA 125 Testing Market Diagnostics  

 Sales by Major Supplier 

 U.S., CEA Testing Market Diagnostics  

 Sales by Major Supplier 

 U.S., Ferritin Testing Market  

 Diagnostics Sales by Major Supplier 

 U.S., HCG Testing Market  

 Diagnostics Sales by Major Supplier 

 U.S., Insulin Testing Market  

 Diagnostics Sales by Major Supplier 

 U.S., Parathyroid Hormone Testing Market  

 Diagnostics Sales by Major Supplier 

 U.S., PAP Testing Market Diagnostics  

 Sales by Major Supplier 

 U.S., Progesterone Receptor Testing Market  

 Diagnostics Sales by Major Supplier 

 U.S., PSA Testing Market Diagnostics 

 Sales by Major Supplier