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June 2005 

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Nutrigenomics: 
Impacts on Markets, Diets, and Health

Kathie Wrick, Ph.D., R.D., and Laura Ruth, Ph.D.

New Page 1

Figure 1.1. Relation between Dose of Soluble Fiber and Mean Serum Cholesterol Changes

Figure 1.2. Genetic Influences on the Response of Bone Mineral Density to Caffeine

Figure 1.3. A Pharmacogenomic Value Chain Formed As Genomics Technologies and Services Were Utilized for Drug Development

Figure 1.4. Health Effects of Food Components Are Related Mostly to Specific Interactions on a Molecular Level

Figure 1.5. Genomics Applications to the Food Industry Value Chain

Figure 3.1. Value Chain Driving Golden Rice Development

Figure 4.1. PUFA Biosynthesis Pathway

Figure 4.2. Nutrigenetic Testing Value Chain

Figure 4.3. Consumer Acceptance of Personalized Products

Figure 4.4. Awareness of Specific Uses of Genomics

Figure 4.5. Nutrigenomics Favorability

Figure 4.6. Nutrigenomics: Interest in Specific Products

Figure 4.7. Nutrigenomics: Role of Doctor

Figure 4.8. Nutrigenomics: Purchasing Influences

Figure 4.9. Consumers and Their Health Management: Psychographic Segmentation

Table 2.1. Nutrigenomic Technologies by Market Area

Table 2.2. Microarray Terms

Table 2.3. Applications of Microarray Technologies to Nutrigenomic Research

Table 2.4. Bioinformatic Terms

Table 2.5. Bioinformatic Applications to Nutrigenomic Research

Table 2.6. Technology Comparison of GenMAPP Versus MetaCore

Table 2.7. Cell Culture Terms

Table 2.8. Culture – Nutrigenomic Research Applications

Table 2.9. Genetic Strategy Terms

Table 2.10. Genetic Strategy Nutrigenomic Research Application

Table 2.11. Analytical Techniques Used in Biomarker Identification

Table 2.12. Analytical Methods Used in Metabolomic Research

Table 2.13. Genetic Test Terms

Table 2.14. Nutrigenomic Testing for Diet-Related Chronic Diseases

Table 2.15. More Genetic Test Technologies

Table 2.16. Cardiovascular Nutrigenomic Diagnostic Technology

Table 2.17. Osteoporosis Nutrigenomic Diagnostic Technology

Table 2.18. Immune Health Nutrigenomic Diagnostic Technology

Table 2.19. Detoxification Nutrigenomic Diagnostic Technology

Table 2.20. B Vitamin Use – Diagnostic Technology

Table 2.21. Antioxidant Diagnostic Technology

Table 2.22. Insulin Insensitivity Diagnostic Technology

Table 2.23. Nutrigenomic Diagnostic Technology for Diabetes

Table 2.24. Kidney Disease Nutrigenomic Diagnostic Technology

Table 2.25. Obesity Nutrigenomic Diagnostic Technology

Table 2.26. Familial Hypercholesterolemia Diagnostic Technology

Table 2.27. Metabolic Syndrome Diagnostic Technology

Table 2.28. Non-Specific Disease Diagnostic Technology

Table 2.29. Nutrigenetic Test Gene Glossary

Table 2.30. Selected Ag-Bio Nutrigenomic Projects and Technologies

Table 3.1. Biotechnology by Nutrigenomic Research Application – Nutraceutical

Table 3.2. Biotechnology Applied to Nutrigenomic Research – Pharma Therapeutics/Diagnostics

Table 3.3. Companies Active in Nutrigenetic Testing

Table 3.4. Nutrigenetic Test & Supplement Costs

Table 3.5. Nutrigenetic Testing: What Consumers Would Pay

Table 3.6. Market Estimates for Lipochip

Table 3.7. Nutritional Genomic Patents by Category

Table 3.8. Gene Patents by Company

Table 3.9. Biomarker Patents by Company

Table 3.10. Bioinformatics Patents by Company

Table 3.11. Clinical Diagnostic Technology Patents by Company

Table 3.12. Food and Dietary Ingredient Compound Patents by Company

Table 3.13. Cell Culture/Gene Expression Patent by Company

Table 3.14. Microarray Patents by Company

Table 3.15. Bacteria Application Patent by Company

Table 3.16. Patents by Assignee

Table 3.17. Biotechnology Nutritional Genomic Patents

Table 4.1. Nutrigenetic Testing Sales Methods and Revenue

Table 4.2. Pharmacogenetic Versus Nutrigenetic Clinical Test Cost Comparison

Table 4.3. Issues Raised by Government Policymakers Applicable to DTC Marketing, Advertising of Genetic Tests, Pharmacogenomic Tests and Nutrigenomic Tests

 


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