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September 2006 

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CHI Advances: Tech Update
Proteomics: Current State and Future Directions

Hermann A.M. Mucke, Ph.D.

New Page 1

SECTION 1
Introduction: The Current State of Proteomics Technology

SECTION 2
A Brief History of Proteomics Technology

SECTION 3
General Overview of Proteomics Research Challenges

SECTION 4
Current Technologies

Protein Separation/Sample Enrichment
Liquid Chromatography
Protein Removal
Mass-coded Labeling

SECTION 5
Research Comparing Quantification Methods

Protein Identification and Quantification
Mass Spectrometry
Common MS Instrument Types
Antibody/Protein Array Applications
Protein Indentification and Quantification, Antibodies
Protein-Protein Interaction

SECTION 6
Technical Challenges

Dynamic Range
Albumin Removal

SECTION 7
Selected Research Methods Reports

Protein microarrays
Sample Complexity
Multiphoton Detection

SECTION 8
Selected Product Introductions

Beckman-Coulter
Sigma-Aldrich
Cambrex
Serva Electrophoresis
PerkinElmer
Thermo Electron
Sigma-Aldrich
Agilent Technologies
Bruker Daltonics
KREATECH
Axela Biosensors
Syngene
Sigma-Aldrich

SECTION 9
Selected Deals and Mergers

Combi Matrix\Biodesign Institute
Caprion\ICOS
Affibody\Agilent
PerkinElmer\Agilix
Applied Biosystems\Invitrogen
PerkinElmer\Luminex

SECTION 10
Expert Interviews: Current State and Future Directions

Roger Brent, PhD
Gilbert S. Omenn, MD, PhD
James R. Heath, PhD

SECTION 11
Selected Company Profiles

BiaCore
BioRad
Invitrogen
Luminex
Thermo Electron

APPENDIX
CHI Advances – 2006 Proteomics Survey

References

 

 


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