Outlook for Predictive Safety Technologies

Figure 1.1. Anticipated Breakthroughs Through 2015 

Figure 4.1. Tasks for the National Center for Toxigenomics Research Consortium 

Figure 4.2. Factors Contributing to the Cellular Systems Biology Response in Cytoxicity 

Figure 4.3. Multiplexed Assays: Fingerprints for Cytotoxicity HCS 

Figure 4.4. Screening for Heart Rates 

Figure 5.1. Relative Predictive Value of Predictive Safety Assessment Methods 

Figure 5.2. Complexity of Implementation for Predictive Safety Assessment Methods

Table 2.1. Cost Estimates for a Basic Preclinical Safety Pharmacological Program 

Table 2.2. Examples of Drugs Removed from the World Market 

Table 2.3. In-Life Animal Requirements for a Basic Preclinical Program 

Table 4.1. Selected Manufacturers and Vendors of Rodent and Human Toxicology Arrays