Next-Generation Sequencing: Scientific and Commercial Implications of the $1000 Genome

By Kevin Davies, PhD

TABLES

Table 2.1. Next-Generation Sequencing Technologies

Table 2.2. Features of Major Next-Generation Sequencing Platforms

FIGURES

Figure 2.1. SOLiD: 2 Base Pair Encoding Using 4 Dyes

Figure 2.2. SOLiD: Example of Decoding

Figure 2.3. Apparatus for Single-Molecule Analysis Using Zero-Mode Waveguides

Figure 6.1. Survey Respondents by Sector

Figure 6.2. Primary Involvement in Next-Generation Sequencing

Figure 6.3. Application of Next-Generation Sequencing

Figure 6.4. Organisms Sequenced Using New Platform(s)

Figure 6.5. Active Use of Next-Generation Sequencing Systems

Figure 6.6. Most Promising Platform

Figure 6.7. Chief Application of Next-Generation Sequencing

Figure 6.8. Areas of Disease Research to Benefit from Next-Generation Sequencing

Figure 6.9. Chief Technical Concerns about Next-Generation Sequencing

Figure 6.10. Assessment of Current Platform Costs

Figure 6.11. Cost of Full Human Genome Sequencing by 2010

Figure 6.12. Dominant Platform

Figure 6.13. Future Role of Sanger (Capillary) Sequencing

Figure 6.14. Opinions Concerning GINA