INFLAMMATORY DIRECTIONS: STRATEGIES FOR SIX DISEASES WITH UNMET NEEDS

By Mark C. Via

FIGURES

Figure 1.1. The Immune Response

Figure 2.1. Pathogenesis of Rheumatoid Arthritis

Figure 2.2. Pathogenesis of Inflammatory Bowel Disease

Figure 2.3. Pathophysiology of Psoriasis

Figure 2.4. The Allergic Cascade in Asthma

Figure 3.1. Therapeutic Management of Rheumatoid Arthritis

Figure 3.2. Therapeutic Management of Lupus Nephritis with Severe Renal Involvement

TABLES

Table 2.1. ACR Criteria for Diagnosis of Systemic Lupus Erythematosus

Table 3.1. Conventional Treatment Regimens for Crohn’s Disease and Ulcerative Colitis

Table 3.2. Stepwise Approach to Managing Asthma

Table 4.1. Clinical Programs in Inflammatory Diseases Suspended Since 2002

Table 4.2. Drugs in Clinical Trials for Rheumatoid Arthritis

Table 4.3. Drugs in Clinical Trials for Inflammatory Bowel Disease

Table 4.4. Drugs in Clinical Trials for Psoriasis

Table 4.5. Drugs in Clinical Trials for Lupus

Table 4.6. Drugs in Clinical Trials for Multiple Sclerosis

Table 4.7. Drugs in Clinical Trials for Asthma